Dermatologica Sinica (Dec 2016)

Systemic follicular lymphoma mimicking typical histological pattern of mycosis fungoides

  • Yi-Wen Kuo,
  • Pei-Ying Hsieh,
  • Cheng-Hsiang Hsiao,
  • Po-Hsuan Lu

DOI
https://doi.org/10.1016/j.dsi.2016.03.003
Journal volume & issue
Vol. 34, no. 4
pp. 200 – 204

Abstract

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Follicular lymphoma (FL) is typically presented in the form of lymphadenopathy, hepatosplenomegaly, and bone marrow infiltration. Herein, we report a case of systemic FL first presenting with a generalized asymptomatic rash with histological features of a superficial band-like lymphoid infiltrate and areas of epidermotropism. Immunohistological studies revealed a B-cell lineage of the atypical lymphocytes. FL was diagnosed through a flow cytometric analysis of the bone marrow aspirate. As per our literature review, this is the first reported case of a systemic FL with secondary cutaneous involvement mimicking the stereotypical histological pattern of mycosis fungoides.

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