Effect of different grade of primary hypertension on corneal endothelial cells

Guoji Yanke Zazhi. 2015;15(12):2140-2142 DOI 10.3980/j.issn.1672-5123.2015.12.31

 

Journal Homepage

Journal Title: Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)

Publisher: Press of International Journal of Ophthalmology (IJO PRESS)

Society/Institution: Chinese Medical Association Xi’an Branch

LCC Subject Category: Medicine: Ophthalmology

Country of publisher: China

Language of fulltext: English

Full-text formats available: PDF

 

AUTHORS


Lin Wang (Department of Ophthalmology,Shenyang the Fourth Hospital of People, Shenyang 110031, Liaoning Province, China)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 24 weeks

 

Abstract | Full Text

AIM:To investigate the effect of different stage of primary hypertension on corneal endothelial cells by Specular Microscope. <p>METHODS:Case-control study was taken. The case group included 71 patients(142 eyes)diagnosed with primary hypertension, including 22 patients(44 eyes)in group stage 1, 23 patients(46 eyes)in group stage 2 and 26 patients(52 eyes)in group stage 3. The control group included 69 healthy subjects(138 eyes). There was no statistical differences in gender and age(<i>P</i>>0.05), and no systemic or eye disease for the both groups.Statistical analysis was made on the corneal endothelial cells including average cell area, average cell density, coefficient of variation and percentage of hexagonal cells. <p>RESULTS:Average cell area and average cell density had no statistical differences for both groups. Coefficient of variation increased(<i>t</i>=3.34, <i>P</i><0.05)and percentage of hexagonal cells decreased(<i>t</i>=-2.07, <i>P</i><0.05)for case group. There was no significant difference on average cell area and average cell density among the three subgroups in case group(<i>P</i>>0.05). There was significant differences for coefficient of variation and percentage of hexagonal cells(<i>P</i> <0.05)among the three subgroups.. <p>CONCLUSION:Compared with the control group, corneal endothelial cells of patients with primary hypertension increases significantly on coefficient of variation and decreases on percentage of hexagonal cells. Patients with different hypertension grades have different coefficient of variation and percentage of hexagonal cells.