Effects of Combined Inhalation of Coal Dust and Cigarette Smoking on Haematobiochemical Parameters

Abstract

Aim of this study was have to known an effect of inhaled particulate matter coal dust and smoking on hematobiochemical profile of worker in coal analysis laboratoy. Twenty nine workers, were randomly divided into three groups, one control group (n=5), one group who exposed to coal dust but non smoking (CDNS) (n=15), and one group exposed to coal dust and smoking (CDS) (n=9). Control group are subject who working in administrative division which none exposed to coal dust. Exposed group are subject who working in coal dust material analysis who divided into smoker and non smoker. The duration of working are less than 10 years. Mean of eosinofil and monocytes counts were decreased significantly in both of coal dust exposure compared to control group (p<0.05). Segmental neutrophil counts was increase significantly in coal dust exposure group with or without smoking compared to control group (p<0.05). The level of erythocytre sedimentation rate (ESR) was decreased significantly in CDNS group compared to control group (p<0.05). Combined inhalation of coal dust and cigarette smoking changes cellular imune system such as decreasing of eosinophil and monocytes counts also increasing of segmental neutrophil. Beside that, this exposure also induces acute phase process of inflammation. [Cukurova Med J 2013; 38(4.000): 547-552]

Keywords

• worker; coal dust analysis laboratory; hematological; biochemical