International Journal of Molecular Sciences (Jan 2021)

A Closer Look at the Cellular and Molecular Components of the Deep/Muscular Fasciae

  • Caterina Fede,
  • Carmelo Pirri,
  • Chenglei Fan,
  • Lucia Petrelli,
  • Diego Guidolin,
  • Raffaele De Caro,
  • Carla Stecco

DOI
https://doi.org/10.3390/ijms22031411
Journal volume & issue
Vol. 22, no. 3
p. 1411

Abstract

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The fascia can be defined as a dynamic highly complex connective tissue network composed of different types of cells embedded in the extracellular matrix and nervous fibers: each component plays a specific role in the fascial system changing and responding to stimuli in different ways. This review intends to discuss the various components of the fascia and their specific roles; this will be carried out in the effort to shed light on the mechanisms by which they affect the entire network and all body systems. A clear understanding of fascial anatomy from a microscopic viewpoint can further elucidate its physiological and pathological characteristics and facilitate the identification of appropriate treatment strategies.

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