Clinical Endoscopy (Jul 2017)

Necrotizing Pancreatitis: Current Management and Therapies

  • Christine Boumitri,
  • Elizabeth Brown,
  • Michel Kahaleh

DOI
https://doi.org/10.5946/ce.2016.152
Journal volume & issue
Vol. 50, no. 4
pp. 357 – 365

Abstract

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Acute necrotizing pancreatitis accounts for 10% of acute pancreatitis (AP) cases and is associated with a higher mortality and morbidity. Necrosis within the first 4 weeks of disease onset is defined as an acute necrotic collection (ANC), while walled off pancreatic necrosis (WOPN) develops after 4 weeks of disease onset. An infected or symptomatic WOPN requires drainage. The management of pancreatic necrosis has shifted away from open necrosectomy, as it is associated with a high morbidity, to less invasive techniques. In this review, we summarize the current management and therapies for acute necrotizing pancreatitis.

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