Saccharomyces cerevisiae-Based Probiotics as Novel Antimicrobial Agents to Prevent and Treat Vaginal Infections

Roberta Gaziano; Samuele Sabbatini; Elena Roselletti; Stefano Perito; Claudia Monari

doi:10.3389/fmicb.2020.00718

Frontiers in Microbiology (Apr 2020)

Saccharomyces cerevisiae-Based Probiotics as Novel Antimicrobial Agents to Prevent and Treat Vaginal Infections

Roberta Gaziano,
Samuele Sabbatini,
Elena Roselletti,
Stefano Perito,
Claudia Monari

Affiliations

Roberta Gaziano: Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy
Samuele Sabbatini: Department of Medicine, Medical Microbiology Section, University of Perugia, Perugia, Italy
Elena Roselletti: Department of Medicine, Medical Microbiology Section, University of Perugia, Perugia, Italy
Stefano Perito: Department of Medicine, Medical Microbiology Section, University of Perugia, Perugia, Italy
Claudia Monari: Department of Medicine, Medical Microbiology Section, University of Perugia, Perugia, Italy

DOI: https://doi.org/10.3389/fmicb.2020.00718
Journal volume & issue: Vol. 11

Abstract

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Vaginal infections affect 70% of women during their lifetimes and account for millions of annual doctors’ visits. These infections are predominantly represented by vulvovaginal candidiasis (VVC) and bacterial vaginosis (BV). Although standard antimicrobial agents remain the major strategy for the prevention and treatment of vaginal infections, both VVC and BV are difficult to treat due to high rates of resistance and recurrence, high probability of complications, and negative effects on the vaginal microbiota. This review focuses on a new approach of yeast-based probiotics for the prevention and/or treatment of these common vaginal infections.

Published in Frontiers in Microbiology

ISSN: 1664-302X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.frontiersin.org/journals/microbiology

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Abstract

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