17β-estradiol biosensors based on different bioreceptors and their applications

Xinyi Wang; Xinyi Wang; Fanli Kong; Fanli Kong; Yaoyao Liu; Yaoyao Liu; Shiya Lv; Shiya Lv; Kui Zhang; Kui Zhang; Shutong Sun; Shutong Sun; Juntao Liu; Juntao Liu; Mixia Wang; Mixia Wang; Xinxia Cai; Xinxia Cai; Hongyan Jin; Shi Yan; Jinping Luo; Jinping Luo

doi:10.3389/fbioe.2024.1347625

Frontiers in Bioengineering and Biotechnology (Jan 2024)

17β-estradiol biosensors based on different bioreceptors and their applications

Xinyi Wang,
Xinyi Wang,
Fanli Kong,
Fanli Kong,
Yaoyao Liu,
Yaoyao Liu,
Shiya Lv,
Shiya Lv,
Kui Zhang,
Kui Zhang,
Shutong Sun,
Shutong Sun,
Juntao Liu,
Juntao Liu,
Mixia Wang,
Mixia Wang,
Xinxia Cai,
Xinxia Cai,
Hongyan Jin,
Shi Yan,
Jinping Luo,
Jinping Luo

Affiliations

Xinyi Wang: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Xinyi Wang: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Fanli Kong: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Fanli Kong: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Yaoyao Liu: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Yaoyao Liu: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Shiya Lv: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Shiya Lv: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Kui Zhang: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Kui Zhang: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Shutong Sun: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Shutong Sun: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Juntao Liu: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Juntao Liu: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Mixia Wang: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Mixia Wang: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Xinxia Cai: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Xinxia Cai: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China
Hongyan Jin: Obstetrics and Gynecology Department, Peking University First Hospital, Beijing, China
Shi Yan: Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China
Jinping Luo: State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China
Jinping Luo: School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, China

DOI: https://doi.org/10.3389/fbioe.2024.1347625
Journal volume & issue: Vol. 12

Abstract

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17β-Estradiol (E2) is a critical sex steroid hormone, which has significant effects on the endocrine systems of both humans and animals. E2 is also believed to play neurotrophic and neuroprotective roles in the brain. Biosensors present a powerful tool to detect E2 because of their small, efficient, and flexible design. Furthermore, Biosensors can quickly and accurately obtain detection results with only a small sampling amount, which greatly meets the detection of the environment, food safety, medicine safety, and human body. This review focuses on previous studies of biosensors for detecting E2 and divides them into non-biometric sensors, enzyme biosensors, antibody biosensors, and aptamer biosensors according to different bioreceptors. The advantages, disadvantages, and design points of various bioreceptors for E2 detection are analyzed and summarized. Additionally, applications of different bioreceptors of E2 detection are presented and highlight the field of environmental monitoring, food and medicine safety, and disease detection in recent years. Finally, the development of E2 detection by biosensor is prospected.

Published in Frontiers in Bioengineering and Biotechnology

ISSN: 2296-4185 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Technology: Chemical technology: Biotechnology
Website: http://www.frontiersin.org/bioengineering_and_biotechnology

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