Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry (Feb 2011)

ANALYSE QUANTITATIVE PAR FLUORESCENCE DE VITAMINE E DANS LES FORMULES PHARMACEUTIQUES

  • Alexandru Stoica,
  • Mihaela F. Maria,
  • Mihaela Ilie,
  • Ana M. Hossu

Journal volume & issue
Vol. 12, no. 1
pp. 25 – 32

Abstract

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Many applications of this technique are encountered in the determination of organic compounds or molecules of biological importance, such as thiamin, riboflavin, adrenalin, cholesterol, paraffins or certain medications and drugs. Fluorimetric determinations are sensitive and selective and could determine the concentrations up to 10-10 g•mL-1, which corresponds to a sensitivity of 100 - 1000 times higher than most methods based on molecular absorption.This paper has developed two methods for spectrofluorimetric determination of vitamin E in pharmaceutical formulations (soft gelatin capsules of vitamin E) and serum.

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