In Vivo Screen Identifies Liver X Receptor Alpha Agonism Potentiates Sorafenib Killing of Hepatocellular Carcinoma

• A.M. Vázquez Salgado,
• M.E. Preziosi,
• D. Yin,
• A. Holczbauer,
• A.M. Zahm,
• N. Erez,
• J. Kieckhaefer,
• D. Ackerman,
• T.P. Gade,
• K.H. Kaestner,
• K.J. Wangensteen

Affiliations

A.M. Vázquez Salgado

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

M.E. Preziosi

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

D. Yin

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

A. Holczbauer

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

A.M. Zahm

Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania

N. Erez

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

J. Kieckhaefer

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

D. Ackerman

Penn Image-Guided Interventions Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania

T.P. Gade

Penn Image-Guided Interventions Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania

K.H. Kaestner

Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania

K.J. Wangensteen

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania; Correspondence: Address correspondence to: Kirk J. Wangensteen, MD, PhD, Mayo Clinic, 200 First ST SW, Rochester, MN 55905