Nature Communications (Jun 2019)
Conformational manipulation of scale-up prepared single-chain polymeric nanogels for multiscale regulation of cells
- Xiaoyu Chen,
- Rui Li,
- Siu Hong Dexter Wong,
- Kongchang Wei,
- Miao Cui,
- Huaijun Chen,
- Yuanzhang Jiang,
- Boguang Yang,
- Pengchao Zhao,
- Jianbin Xu,
- Heng Chen,
- Chao Yin,
- Sien Lin,
- Wayne Yuk-Wai Lee,
- Yihan Jing,
- Zhen Li,
- Zhengmeng Yang,
- Jiang Xia,
- Guosong Chen,
- Gang Li,
- Liming Bian
Affiliations
- Xiaoyu Chen
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Rui Li
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Siu Hong Dexter Wong
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Kongchang Wei
- Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles
- Miao Cui
- Beijing Genomic Institute-Shenzhen
- Huaijun Chen
- The State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University
- Yuanzhang Jiang
- Institute of Textiles & Clothing, The Hong Kong Polytechnic University
- Boguang Yang
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Pengchao Zhao
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Jianbin Xu
- Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
- Heng Chen
- Shenzhen Key Laboratory of Special Functional Materials, College of Materials Science and Engineering, Shenzhen University
- Chao Yin
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Sien Lin
- Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital
- Wayne Yuk-Wai Lee
- Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital
- Yihan Jing
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- Zhen Li
- The State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University
- Zhengmeng Yang
- Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital
- Jiang Xia
- Department of Chemistry, The Chinese University of Hong Kong
- Guosong Chen
- The State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University
- Gang Li
- Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital
- Liming Bian
- Department of Biomedical Engineering, The Chinese University of Hong Kong
- DOI
- https://doi.org/10.1038/s41467-019-10640-z
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 12
Abstract
Cyclized or folded single-chain polymeric nano-objects are generally produced with low efficiency. Here, the authors have scaled up the preparation of supramolecular single-chain nanogels by RAFT polymerizations and applied the dynamic supramolecular single-chain nanogels to regulate cell behaviours at varying scales.
