Discover Oncology (Feb 2023)

Metabolic syndrome and thyroid Cancer: risk, prognosis, and mechanism

  • Ling-Rui Li,
  • Jun-Long Song,
  • Han-Qing Liu,
  • Chuang Chen

DOI
https://doi.org/10.1007/s12672-022-00599-7
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 16

Abstract

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Highlights Met S and its components were associated with an increased risk and aggressiveness of thyroid cancer. The obese males have a tighter association with thyroid cancer, and females have a higher thyroid cancer risk among diabetes. Thyroid-stimulating hormones may be a switch for thyroid carcinogenesis. Insulin resistance plays a critical role in the development of thyroid cancer. Abnormal levels of adipocytokines and blood pressure related regulatory hormone assist in accelerating thyroid cancer progression.

Keywords