Second line anti-cancer therapy for metastatic colorectal cancer: treatment strategy

Abstract

Colorectal cancer is one of the most widespread cancers globally. Over the past decade, there has been a significant progress in the treatment of metastatic colorectal cancer. However, an increase in the range of effective anticancer drugs is associated with a number of difficulties in determining the adequate drug treatment regimens for patients with metastatic colorectal cancer. The article describes the current aspects of II line treatment of metastatic colorectal cancer, guidelines for the selection of chemotherapy regimens and appointment of targeted drugs.

Keywords

• колоректальный рак ii линия терапии иринотекан
• оксалиплатин таргетная терапия бевацизумаб
• афлиберцепт цетуксимаб
• панитумумаб
• colorectal cancer
• ii line treatment
• irinotecan
• oxaliplatin
• targeted therapy
• bevacizumab
• aflibercept
• cetuximab
• pan