PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors

Alexander Lin, MD; John H. C. Chang, MD; Ryan S. Grover, MD; Frank J. P. Hoebers, MD, PhD; Upendra Parvathaneni, MBBS, FRANZCR; Samir H. Patel, MD; Juliette Thariat, MD, PhD; David J. Thomson, MA, MD, FACR; Johannes A. Langendijk, MD, PhD; Steven J. Frank, MD; on behalf of the International Particle Therapy Co-operative Group (PTCOG) Head and Neck Subcommittee

doi:10.14338/IJPT-20-00071.1

International Journal of Particle Therapy (Jun 2021)

PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors

Alexander Lin, MD,
John H. C. Chang, MD,
Ryan S. Grover, MD,
Frank J. P. Hoebers, MD, PhD,
Upendra Parvathaneni, MBBS, FRANZCR,
Samir H. Patel, MD,
Juliette Thariat, MD, PhD,
David J. Thomson, MA, MD, FACR,
Johannes A. Langendijk, MD, PhD,
Steven J. Frank, MD,
on behalf of the International Particle Therapy Co-operative Group (PTCOG) Head and Neck Subcommittee

Affiliations

Alexander Lin, MD: 1 University of Pennsylvania, Philadelphia, PA, USA
John H. C. Chang, MD: 2 Oklahoma Proton Center, Oklahoma City, OK, USA
Ryan S. Grover, MD: 3 University of California-San Diego, San Diego, CA, USA
Frank J. P. Hoebers, MD, PhD: 4 Department of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
Upendra Parvathaneni, MBBS, FRANZCR: 5 University of Washington, Seattle, WA, USA
Samir H. Patel, MD: 6 Mayo Clinic, Scottsdale, AZ, USA
Juliette Thariat, MD, PhD: 7 Radiation Oncology Department, François Baclesse Center/ARCHADE, Normandy University, Caen, France
David J. Thomson, MA, MD, FACR: 8 The Christie NHS Foundation Trust, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom
Johannes A. Langendijk, MD, PhD: 9 Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Steven J. Frank, MD: 10 The University of Texas MD Anderson Cancer Center, Houston, TX, USA
on behalf of the International Particle Therapy Co-operative Group (PTCOG) Head and Neck Subcommittee

DOI: https://doi.org/10.14338/IJPT-20-00071.1
Journal volume & issue: Vol. 8, no. 1
pp. 84 – 94

Abstract

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Purpose: Radiation therapy is a standard modality in the treatment for cancers of the head and neck, but is associated with significant short- and long-term side effects. Proton therapy, with its unique physical characteristics, can deliver less dose to normal tissues, resulting in fewer side effects. Proton therapy is currently being used for the treatment of head and neck cancer, with increasing clinical evidence supporting its use. However, barriers to wider adoption include access, cost, and the need for higher-level evidence. Methods: The clinical evidence for the use of proton therapy in the treatment of head and neck cancer are reviewed here, including indications, advantages, and challenges. Results: The Particle Therapy Cooperative Group Head and Neck Subcommittee task group provides consensus guidelines for the use of proton therapy for head and neck cancer. Conclusion: This report can be used as a guide for clinical use, to understand clinical trials, and to inform future research efforts.

Published in International Journal of Particle Therapy

ISSN: 2331-5180 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine; Science: Physics: Nuclear and particle physics. Atomic energy. Radioactivity
Website: https://www.sciencedirect.com/journal/international-journal-of-particle-therapy

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Abstract

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