Thioketone-directed rhodium(I) catalyzed enantioselective C-H bond arylation of ferrocenes

Zhong-Jian Cai; Chen-Xu Liu; Qiang Wang; Qing Gu; Shu-Li You

doi:10.1038/s41467-019-12181-x

Nature Communications (Sep 2019)

Thioketone-directed rhodium(I) catalyzed enantioselective C-H bond arylation of ferrocenes

Zhong-Jian Cai,
Chen-Xu Liu,
Qiang Wang,
Qing Gu,
Shu-Li You

Affiliations

Zhong-Jian Cai: State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Chen-Xu Liu: State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Qiang Wang: State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Qing Gu: State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Shu-Li You: State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

DOI: https://doi.org/10.1038/s41467-019-12181-x
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 8

Abstract

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The development of straightforward methods for the synthesis of planar chiral ferrocenes remains highly challenging. Here, the authors report a rhodium(I)/phosphonate-catalyzed thioketone-directed enantioselective C-H bond arylation reaction for the synthesis of chiral planar ferrocenes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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