ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis

Caitríona M. Collins; Beatrice Malacrida; Colin Burke; Patrick A. Kiely; Elaine M. Dunleavy

doi:10.1038/s41467-018-05093-9

Nature Communications (Jul 2018)

ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis

Caitríona M. Collins,
Beatrice Malacrida,
Colin Burke,
Patrick A. Kiely,
Elaine M. Dunleavy

Affiliations

Caitríona M. Collins: Centre for Chromosome Biology, Biomedical Sciences, National University of Ireland Galway
Beatrice Malacrida: Graduate Entry Medical School and Health Research Institute, University of Limerick
Colin Burke: Centre for Chromosome Biology, Biomedical Sciences, National University of Ireland Galway
Patrick A. Kiely: Graduate Entry Medical School and Health Research Institute, University of Limerick
Elaine M. Dunleavy: Centre for Chromosome Biology, Biomedical Sciences, National University of Ireland Galway

DOI: https://doi.org/10.1038/s41467-018-05093-9
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 11

Abstract

Read online

The histone H3 CENP-A is known to play a role during meiosis but its role in the testes in the fly is unknown. Here, the authors identify the mitochondrial metabolic protein complex ATP synthase F1 as interacting with CENP-A, promoting centromere cohesion during meiosis and affecting fly fertility.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal