Data of postoperative complications related to fibrinogen-to-albumin ratio in pancreatic resections
V. La Vaccara,
R. Cammarata,
A. Coppola,
T. Farolfi,
C. Cascone,
S. Angeletti,
G. Maltese,
R. Coppola,
D. Caputo
Affiliations
V. La Vaccara
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy
R. Cammarata
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy; Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy
A. Coppola
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy; Corresponding author.
T. Farolfi
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy; Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy
C. Cascone
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy; Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy
S. Angeletti
Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy; Unit of Clinical Laboratory Science, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy
G. Maltese
Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy
R. Coppola
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy; Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy
D. Caputo
General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy; Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, Rome 00128, Italy
Pancreatic surgery is one of the surgeries burdened with the highest mortality and morbidity rate. This is due both to the aggressive biological nature of the pathology affecting the organ and to the technical difficulties associated with surgery. A further aspect on which research is focusing is represented by inflammation related to oncological pathology. Inflammation plays an important role in tumor progression, and growing evidence has confirmed that the fibrinogen-to-albumin ratio (FAR) is an important prognostic factor for overall survival (OS) in malignant tumors.Inflammatory markers had demonstrated also a role in the prediction of postoperative complication after pancreatic surgery.We speculate that FAR, as an easily available, cost-effective, and non-invasive prognostic indicator for pancreatic cancer patients, could help to identify patients at increased risk of postoperative pancreatic fistula (POPF). We therefore retrospectively analyzed the data relating to 117 pancreatic resections relating direct and indirect markers of inflammation with the incidence of post-operative complications.
