Technology in Cancer Research & Treatment (Apr 2023)

Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy

  • Mingdian Tan PhD,
  • Yizhi Ge MD, PhD,
  • Xiaogang Wang Bsc,
  • Yan Wang PhD,
  • Yi Liu MD, PhD,
  • Feng He PhD,
  • Hongqi Teng PhD

DOI
https://doi.org/10.1177/15330338231171463
Journal volume & issue
Vol. 22

Abstract

Read online

In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite the growing interest in EVs, many questions still need to be addressed before they can be practically applied in clinical settings. This paper aims to review EVs’ isolation methods, structure research, the roles of EVs in tumorigenesis and their mechanisms in multiple types of tumors, their potential application in drug delivery, and the expectations for their future in clinical research.