Pairing off: a bottom‐up approach to the human gut microbiome

Abstract

Abstract The human gut microbiome has been implicated in a variety of health outcomes, and extensive research has aimed to understand its composition and function, primarily via metagenomic analyses. An examination of how the microbiome develops and interacts through interspecies competition and cooperation has been lacking so far. In their recent work, Venturelli et al (2018) build a synthetic gut community and accurately predict its dynamics with a simple network of pairwise interactions.