Histiocytic Sarcoma of Nasal Cavity: A Case Report

Abstract

Histiocytic sarcoma is a rare hematopoietic malignancy that originates from histiocytes, and may involve lymph nodes and extranodal sites such as the spleen, head and neck, skeleton, liver, breast, bone marrow, mediastinum, pancreas, skin, lung, kidney, central nervous system, testis, gastrointestinal tract, and uterus. The involvement of the nasal cavity is considered extremely rare. The prognosis is poor, even with chemotherapy, and the survival time is usually two years. We report the case of a 16-year-old-male with primary histiocytic sarcoma of the nasal cavity. The diagnosis was based on classical histopathology and immunohistochemical findings. This malignancy has not shown consistent satisfactory responses to chemotherapy regimens.

Keywords

• Nasal cavity
• Immunohistochemistry
• Chemotherapy
• Histiocytic sarcoma