Late Diagnosis of Disseminated <i>Sporothrix brasiliensis</i> Infection with Bone Marrow Involvement in an HIV-Negative Patient
Vanessa Caroline Randi Magalhães,
Salene Angelini Colombo,
Gustavo José Cota Freitas,
Alexandre Sampaio Moura,
Flávia Cardoso Lopez Vieira,
Ana Cláudia Lyon,
Maria Isabel Azevedo,
Nalu Teixeira de Aguiar Peres,
Daniel Assis Santos
Affiliations
Vanessa Caroline Randi Magalhães
Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil
Salene Angelini Colombo
Department of Preventive Veterinary Medicine, School of Veterinary, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil
Gustavo José Cota Freitas
Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil
Alexandre Sampaio Moura
Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais (FHEMIG), R. Dr. Cristiano Rezende, 2213, Belo Horizonte 30622-020, Brazil
Flávia Cardoso Lopez Vieira
Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais (FHEMIG), R. Dr. Cristiano Rezende, 2213, Belo Horizonte 30622-020, Brazil
Ana Cláudia Lyon
Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais (FHEMIG), R. Dr. Cristiano Rezende, 2213, Belo Horizonte 30622-020, Brazil
Maria Isabel Azevedo
Department of Preventive Veterinary Medicine, School of Veterinary, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil
Nalu Teixeira de Aguiar Peres
Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil
Daniel Assis Santos
Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil
Sporotrichosis is a fungal disease that causes symptoms similar to those of other infectious and non-infectious diseases, making diagnosis difficult and challenging. Here, we report a case of an HIV-negative patient presenting disseminated sporotrichosis with widespread cutaneous lesions mimicking pyoderma gangrenosum, with bone marrow infection, pancytopenia, and hemophagocytic syndrome. However, all the clinical manifestations and a bacterial coinfection delayed the request for a fungal diagnosis. Therefore, sporotrichosis should always be investigated in patients from endemic areas presenting with widespread cutaneous lesions associated with pancytopenia.