The role of matrix metalloproteinases and vascular grouth facrors in differentional diagnostic of prostate’s diseases

Abstract

The aim of this study was to determine of TRF1, MMP-7, FLT-1, KDR and VEGF mRNA expression levels obtained from prostate biopsies samples of patients with benign prostatic hyperplasia, prostate cancer and healthy men without prostate pathology. It was demonstrated that detection of TRF1, FLT-1, KDR and MMP-7 expression levels correlations and TRF1/MMP-7 index was criteria of different way for different prostate neoplasm diagnostics.

Keywords

• рак предстательной железы
• мРНК
• сосудистый фактор роста
• биопсия предстательной железы