Journal of Functional Biomaterials (Nov 2019)

Simulated Performance of a Xenohybrid Bone Graft (SmartBone<sup>®</sup>) in the Treatment of Acetabular Prosthetic Reconstruction

  • Carlo Francesco Grottoli,
  • Alberto Cingolani,
  • Fabio Zambon,
  • Riccardo Ferracini,
  • Tomaso Villa,
  • Giuseppe Perale

DOI
https://doi.org/10.3390/jfb10040053
Journal volume & issue
Vol. 10, no. 4
p. 53

Abstract

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Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch−Schneider ring). Moreover, valid alternatives and less invasive techniques still need to be supported by novel material development. In this work, we evaluated the performance of SmartBone®, a xenohybrid bone graft composed of a bovine bone matrix reinforced with biodegradable polymers and collagen, as an effective support in acetabular prosthesis reconstruction. Specifically, the material’s mechanical properties were experimentally determined (E = ~1.25 GPa, Ef = ~0.34 GPa, and Et = ~0.49 GPa) and used for simulation of the hip joint system with a SmartBone® insert. Moreover, a comparison with a similar case treated with a Burch−Schneider ring was also conducted. It was found that it is possible to perform THA revision surgeries without the insertion of an invasive metal support and it can be nicely combined with SmartBone®’s osteointegration characteristics. The material can withstand the loads independently (σmax = ~12 MPa) or be supported by a thinner titanium plate in contact with the bone in the worst cases. This way, improved bone regeneration can be achieved.

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