Long non-coding RNA TUG1 aggravates cerebral ischemia and reperfusion injury by sponging miR-493-3p/miR-410-3p
Du Jinlong,
Li Wenjing,
Wang Bing
Affiliations
Du Jinlong
Department of Critical Care Medicine, Jingzhou Central Hospital, The Second Clinical Medical College of Yangtze University, Jingzhou, Hubei, 434020, China
Li Wenjing
Department of Ultrasound, Jingzhou Central Hospital, The Second Clinical Medical College of Yangtze University, Jingzhou, Hubei, 434020, China
Wang Bing
Department of Critical Care Medicine, Jingzhou Central Hospital, The Second Clinical Medical College of Yangtze University, Jingzhou, Hubei, 434020, China
Cerebral ischemia and reperfusion injury (CIRI) affects bodily function by causing irreversible damage to brain cells. The diverse pathophysiological course factors hinder the research work to go deeper. Long noncoding RNA taurine-upregulated gene 1 (TUG1) has been reported to be related to CIRI. This study explored the undefined regulatory pathway of TUG1 in CIRI.