Long non-coding RNA TUG1 aggravates cerebral ischemia and reperfusion injury by sponging miR-493-3p/miR-410-3p

Du Jinlong; Li Wenjing; Wang Bing

doi:10.1515/med-2021-0253

Open Medicine (Jun 2021)

Long non-coding RNA TUG1 aggravates cerebral ischemia and reperfusion injury by sponging miR-493-3p/miR-410-3p

Du Jinlong,
Li Wenjing,
Wang Bing

Affiliations

Du Jinlong: Department of Critical Care Medicine, Jingzhou Central Hospital, The Second Clinical Medical College of Yangtze University, Jingzhou, Hubei, 434020, China
Li Wenjing: Department of Ultrasound, Jingzhou Central Hospital, The Second Clinical Medical College of Yangtze University, Jingzhou, Hubei, 434020, China
Wang Bing: Department of Critical Care Medicine, Jingzhou Central Hospital, The Second Clinical Medical College of Yangtze University, Jingzhou, Hubei, 434020, China

DOI: https://doi.org/10.1515/med-2021-0253
Journal volume & issue: Vol. 16, no. 1
pp. 919 – 930

Abstract

Read online

Cerebral ischemia and reperfusion injury (CIRI) affects bodily function by causing irreversible damage to brain cells. The diverse pathophysiological course factors hinder the research work to go deeper. Long noncoding RNA taurine-upregulated gene 1 (TUG1) has been reported to be related to CIRI. This study explored the undefined regulatory pathway of TUG1 in CIRI.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

About the journal

Abstract

Keywords