Фармакокинетика и Фармакодинамика (May 2022)

Application of the <i>AlphaScreen</i> and <i>AlphaLisa</i> method in drug development and pharmacokinetic studies

  • R. T. Mukhametshina,
  • S. D. Kopein,
  • V. M. Simonov

DOI
https://doi.org/10.37489/2587-7836-2022-1-44-54
Journal volume & issue
Vol. 0, no. 1
pp. 44 – 54

Abstract

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Drug development requires high-tech, simple, and sensitive methods. AlphaLISA method was announced as a universal method that would fit the listed criteria. However, research of other works on the pharmacokinetics of drugs related to this method showed a small number of pharmacokinetic studies in clinical trials. In this review, we focused on not only the positive aspects of the Alpha method, but also its disadvantages.

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