Contemporary Approach to Antibiotic Therapy of Urinary Tract Infection

Abstract

Urinary tract infection (UTI) is a frequent infectious disease or complication of hospital stay. The effectiveness and the recovery speed of the patient depends on the correct choice of antibacterial drug for the treatment of UTI. The choice of antibacterial therapy in the treatment of UTIs should be dictated by the predicted uropathogen flora. Since it is necessary to start treatment before obtaining the results of urine culture, UTI therapy uses empirical treatment with broad-spectrum antibiotics. However, this leads to a very rapid increase in the resistance of microorganisms to antibiotics. To reduce this effect, as well as to impove the effectiveness of treatment, it is necessary to put forward a hypothesis about the proposed microorganism which caused the UTI as precisely as possible and to try to prescribe the most suitable antibiotic. The clinical situation in which the UTI occurred may determine a probable pathogen, which will be the basis for the choice of antibiotic therapy. The article offers various therapeutic strategies for treatment of UTI, depending on the proposed bacterial flora, the clinical situation, and the characteristics of the patient.

Keywords

• urinary tract infection
• antibiotic therapy
• antibiotic resistance
• microbiological monitoring