Plastic and Reconstructive Surgery, Global Open (Jan 2024)

Safety and Efficacy of Mucograft Porcine Collagen Bioengineered Acellular Dermal Matrix as a Spacer Graft in Lower Eyelid Elevation Surgery

  • Richard Parker, BMBS, MMed(OphthSc), BEHons/BCom, FRANZCO,
  • Megha Kaushik, MBBS, Bsci(Med)Hons, MPhil, MPH, FRANZCO,
  • Oshin Bansal, MBBS, MD(Ophth), FICO,
  • Daniel G. Ezra, MA(Cantab), MMedEd, MD(Cantab), FRCS, FRCOphth FHEA

DOI
https://doi.org/10.1097/GOX.0000000000005562
Journal volume & issue
Vol. 12, no. 1
p. e5562

Abstract

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Background:. Recent regulatory changes have limited the access to a widely used commercially available bioengineered acellular dermal matrix (BADM) product as a spacer graft in the surgical correction of lower eyelid retraction. We report our off-label usage of Mucograft, a porcine BADM, as an alternative BADM. Methods:. A retrospective review was conducted of patients undergoing bilateral lower lid surgery with Mucograft (12 eyes) at a single institution. Results:. For the six patients, there was a mean lower lid elevation of 1.93 mm, without any serious complications. There was greater elevation of the lower lid position for the Mucograft group compared with four septo-retractor control patients (1.93 versus 0.94mm, P = 0.008). Conclusion:. Mucograft performed satisfactorily, and further investigation is warranted regarding its longer-term safety and efficacy.