CRISPR/Cas9 targeting HIV-1 regulatory genes inactivates latent proviral DNA and prevents new infection in T cell culture with inhibition of viral escape

• Y. Ophinni,
• M. Inoue,
• T. Kotaki,
• M. Kameoka,
• Y. Hayashi

Affiliations

Y. Ophinni

Kobe University, Division of Molecular Medicine & Medical Genetics, Kobe, Japan

M. Inoue

Kobe University, Department of International Health, Graduate School of Health Sciences, Kobe, Japan

T. Kotaki

Kobe University, Department of International Health, Graduate School of Health Sciences, Kobe, Japan

M. Kameoka

Kobe University, Department of International Health, Graduate School of Health Sciences, Kobe, Japan

Y. Hayashi

Kobe University, Division of Molecular Medicine & Medical Genetics, Kobe, Japan