Evaluation of Ocular Surface Disease in Glaucoma Patients Using Topical Antiglaucomatous Agents

Abstract

Aim: Evaluation of ocular surface disease (OSD) in glaucoma patients using topical antiglaucomatous agentsPatients and Method: 159 eyes of 83 patients at the age 18 years or over, who had any types of different glaucoma and had been using antiglaucomatous agents for at least 6 months were included in the study. The Ocular Surface Disease Index (OSDI) questionnaire was filled by asking patients individually. Afterwards, in order to examine ocular surface clinically, patients underwent the Schirmer test(under anesthesia) evaluation, tear break-up time(TBUT) and corneal staining. Results: A total of 159 eyes from 51 male and 32 female patients were included in the study. The average age of men was 64,51 ± 9,07 and the average age of women was 54,32 ± 11,44. Mean duration of medication use of the patients was 6.35 ± 5.63 years. 36.5% of the patients had single medication, 32.1% had two medications, 13.8% had three medications and 17.6% had four medications. Of the patients whose dry eye symptoms were assessed using the OSDI questionnaire, 3.8% were normal, 15.7% were mild, 22.6% were moderate and 57.9% were severe dry eye. The mean OSDI score of all patients was 46.80 ± 19.44. The Schirmer test was found at less than 5 mm in 34.1% of eyes. In terms of TBUT, 52.3% of the eyes were evaluated as mild, 29.5% as moderate, 8.5% as severe. When evaluated for corneal staining, normal staining was observed in 13.2%, slight staining in 39.6%, moderate staining in 23.3% and severe staining in 23.9%. Conclusion: In diagnosing OCD, it would also be beneficial to use a test that includes not only the OSDI questionnaire but also tests showing the quality and stability of the tears.

Keywords

• glokom
• antiglokomatöz i̇laçlar
• oküler yüzey hastalığı
• glaucoma
• antiglaucomatous agents
• ocular surface disease