The kinetics of the reaction of 6-substituted nicotinic acids and some p-substituted benzoic acids with diazodiphenylmethane in various alcohols

Abstract

Rate constants have been determined for the reactions of diazodiphenylmethane with a number of 6-substituted nicotinic acids and p-substituted benzoic acids in twelve alcohols. A comparative study was used to evaluate and compare the Hammett r values and solvent effects. Multiple correlations of the log k values for the reactions of 6-substituted nicotinic acids and p-substituted benzoic acids in 12 alcohols with groups of suitable solvent parameters are very successful. The transmission of electronic effects through the pyridine ring system in compared with that in benzene.

Keywords

• 6-substituted nicotinic acids
• protic solvents
• solvent parameters
• Hammett correlation