Revista de la Sociedad Argentina de Diabetes (Jul 2020)
PREVENTION AND PREDICTION IN DIABETES MELLITUS TYPE 1
Abstract
Type 1 diabetes mellitus (DM1) is a disease characterized by the autoimmune destruction of the beta cell mediated by the attack of cytotoxic T lymphocytes and in which the autoantibodies (GADA, IAA, AI2A and ZnT8A) are markers of it. Since this disease has polygenic bases, the risk of developing DM1 is more frequent in first-degree relatives than in the general population.
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