cutaneous manifestation of mantle cell lymphoma

Abstract

Mantle cell lymphoma (MCL) is a distinct type of non-Hodgkin’s lymphoma that commonly affects extra nodal sites. The most commonly affected sites are bone marrow, gastrointestinal tract and Waldeyer’s ring, however, skin is rarely involved. We report a case of 56 year-old patient with MCL, exhibiting multiple large maculopapular skin rashes and skin ulcers. Histopathological examination demonstrated dilated and congested vessels in the dermis without any atypical cells. Our patient showed significant improvement of skin lesions with a combination chemotherapy and debridement. Awareness of skin manifestations of MCL is essential to establish the diagnosis and for timely administration of appropriate treatment.

Keywords

• mantle cell lymphoma
• skin