Frontiers in Oncology (May 2022)
Research Advances on Anti-Cancer Natural Products
- Meng Guo,
- Jie Jin,
- Dong Zhao,
- Zheng Rong,
- Lu-Qi Cao,
- Ai-Hong Li,
- Xiao-Ying Sun,
- Li-Yi Jia,
- Yin-Di Wang,
- Ling Huang,
- Yi-Heng Li,
- Zhong-Jing He,
- Long Li,
- Rui-Kang Ma,
- Yi-Fan Lv,
- Ke-Ke Shao,
- Hui-Ling Cao,
- Hui-Ling Cao,
- Hui-Ling Cao,
- Hui-Ling Cao
Affiliations
- Meng Guo
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Jie Jin
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Dong Zhao
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Zheng Rong
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Lu-Qi Cao
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Ai-Hong Li
- Shaanxi Key Laboratory of Chinese Herb and Natural Drug Development, Medicine Research Institute, Shaanxi Pharmaceutical Holding Group Co., LTD, Xi’an, China
- Xiao-Ying Sun
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Li-Yi Jia
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Yin-Di Wang
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Ling Huang
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Yi-Heng Li
- College of Life Sciences, Northwest University, Xi’an, China
- Zhong-Jing He
- College of Life Sciences, Northwest University, Xi’an, China
- Long Li
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Rui-Kang Ma
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Yi-Fan Lv
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Ke-Ke Shao
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Hui-Ling Cao
- College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China
- Hui-Ling Cao
- Xi’an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi’an Medical University, Xi’an, China
- Hui-Ling Cao
- Shaanxi Key Laboratory of Chinese Herb and Natural Drug Development, Medicine Research Institute, Shaanxi Pharmaceutical Holding Group Co., LTD, Xi’an, China
- Hui-Ling Cao
- College of Life Sciences, Northwest University, Xi’an, China
- DOI
- https://doi.org/10.3389/fonc.2022.866154
- Journal volume & issue
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Vol. 12
Abstract
Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products were categorized into eight classes according to their chemical structures, including alkaloids, terpenoids and volatile oils, inorganic salts, phenylpropanoids, flavonoids and isoflavones, quinone, saponins and polysaccharides. The review focused on the latest advances in anti-cancer activity of representative natural products for every class. Additionally, anti-cancer molecular mechanism and derivatization of natural products were summarized in detail, which would provide new core structures and new insights for anti-cancer new drug development.
Keywords
