Архивъ внутренней медицины (Dec 2014)

УРОВЕНЬ ЛИПОКАЛИНА В КРОВИ И МОЧЕ У БОЛЬНЫХ ОСТРЫМ КОРОНАРНЫМ СИНДРОМОМ В ЗАВИСИМОСТИ ОТ СТРАТЕГИИ РЕВАСКУЛЯРИЗАЦИИ

  • М. А. Шаленкова,
  • З. Д. Михайлова,
  • П. Ф. Климкин

DOI
https://doi.org/10.20514/2226-6704-2014-0-6-10-13
Journal volume & issue
Vol. 0, no. 6
pp. 10 – 13

Abstract

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S-NGAL and u-NGAL content was examined for 113 acute coronary syndrome (ACS) patients, depending on revascularization strategy. 39 (66,1%) ACS patients had transcutaneous coronary treatment (TCT), 41 myocardial infarction (MI) patients with ST segment rise (MI-STR) had thrombolytic therapy (TLT). Higher s-NGAL and u-NGAL levels were obtained for patients with haemodynamically meaningful stenoses (HMS) of coronary arteries (CA) as compared with patients not having HMS. S-NGAL and u-NGAL content for MI-STR patients was higher for patients receiving non-effective, rather than effective TLT, and for patients with contraindications to TLT. Both s-NGAL and u-NGAL levels were higher for MI-STR patients to whom farmacoinvasive strategy was applied, as compared to using only one revascularization method.

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