Molecules (Apr 2002)

Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents

  • José Dias de Souza Filho,
  • Emanoel de Castro Antunes Felício,
  • Eloi Teixeira César,
  • Richard Nilton Berg,
  • Ana Paula Soares Fontes,
  • Mauro Vieira de Almeida

DOI
https://doi.org/10.3390/70400405
Journal volume & issue
Vol. 7, no. 4
pp. 405 – 411

Abstract

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This work describes the synthesis of seven new platinum complexes having Nbenzyl 1,3-propanediamine derivatives as ligands. They were prepared by the reaction of K2[PtCl4] with the appropriate ligand in water. These complexes are analogs of cisplatin, and are potential antineoplastic agents.

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