Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

Dimitry A Chistiakov; Yuri V Bobryshev; Emil eKozarov; Igor A Sobenin; Alexander Nikolaevich Orekhov

doi:10.3389/fmicb.2014.00781

Frontiers in Microbiology (Jan 2015)

Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

Dimitry A Chistiakov,
Yuri V Bobryshev,
Emil eKozarov,
Igor A Sobenin,
Alexander Nikolaevich Orekhov

Affiliations

Dimitry A Chistiakov: Pirogov Russian State Medical University
Yuri V Bobryshev: University of New South Wales and University of Western Sydney
Emil eKozarov: Columbia University
Igor A Sobenin: Institute of General Pathology and Pathophysiology, Russian Academy of Sciences
Alexander Nikolaevich Orekhov: Institute of General Pathology and Pathophysiology, Russian Academy of Sciences

DOI: https://doi.org/10.3389/fmicb.2014.00781
Journal volume & issue: Vol. 5

Abstract

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The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.

Published in Frontiers in Microbiology

ISSN: 1664-302X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.frontiersin.org/journals/microbiology

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Abstract

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