Бюллетень сибирской медицины (Dec 2006)
Estimation of relations between breathing perception, breathing patterns and the respiratory biomechanics in persons with various ventilator possibilities of the respiratory system at respiratory therapy
Abstract
The data obtained have attributes of fundamental investigation with the evidence-based level C. The relations between the breathing perception, dispnoea, respiratory center (RC) functioning and respiratory mechanics have been studied in healthy persons (HP, n = 20), patients with bronchial asthma (BA, n = 30) and chronic obstructive pulmonary disease (COPD, n = 30) at an electrical stimulation of diaphragm (ESD) and subsequent inhalations of the bronchodilator Berodual. Descriptive, comparative, correlative, canonical, cluster, factorial, regressive and informative analysis of the results has been performed. It has been found that ESD and Berodual have the adaptable action on the sensory parts of the central nervous system (SPCNS) and functioning of RC. On the basis of the correlations obtained, structural models of the functional biomechanical systems of the respiratory system (RS) adjusted by RC, in HP, BA patients and COPD patients are proposed. Peculiarities of the models of functioning SPCNS, RC and RS in HP, BA patients and COPD patients have been described qualitatively.
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