Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report
Ivana Papežíková,
Veronika Piačková,
Iva Dyková,
Ali Asghar Baloch,
Hana Kocour Kroupová,
Eliška Zusková,
Ľubomír Pojezdal,
Hana Minářová,
Eva Syrová,
Hana Banďouchová,
Pavel Hyršl,
Kateřina Matějíčková,
Jiří Pikula,
Miroslava Palíková
Affiliations
Ivana Papežíková
Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech Republic
Veronika Piačková
University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech Republic
Iva Dyková
Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech Republic
Ali Asghar Baloch
University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech Republic
Hana Kocour Kroupová
University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech Republic
Eliška Zusková
University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech Republic
Ľubomír Pojezdal
Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute Brno, 621 00 Brno-Medlánky, Czech Republic
Hana Minářová
Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech Republic
Eva Syrová
Department of Ecology and Diseases of Zoo Animals, Game, Fish and Bees, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno, Palackého tř. 1946/1, 612 42 Brno, Czech Republic
Hana Banďouchová
Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech Republic
Pavel Hyršl
Department of Experimental Biology, Masaryk University, 625 00 Brno, Czech Republic
Kateřina Matějíčková
Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute Brno, 621 00 Brno-Medlánky, Czech Republic
Jiří Pikula
Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech Republic
Miroslava Palíková
Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech Republic
In the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed increased monocyte and decreased lymphocyte counts in CEV-affected fish compared to healthy control fish. Regarding immune system functioning, the present work shows, for the first time, enhanced phagocytic activity in CEV-affected fish. Respiratory burst of phagocytes was strongly increased in diseased fish, the increase being attributed to an increased phagocyte count rather than enhancement of their metabolic activity. The present work also newly shows histopathological changes in the pancreatic tissue of diseased koi.
