Nature Communications (Apr 2020)

Repurposing a chemosensory macromolecular machine

  • Davi R. Ortega,
  • Wen Yang,
  • Poorna Subramanian,
  • Petra Mann,
  • Andreas Kjær,
  • Songye Chen,
  • Kylie J. Watts,
  • Sahand Pirbadian,
  • David A. Collins,
  • Romain Kooger,
  • Marina G. Kalyuzhnaya,
  • Simon Ringgaard,
  • Ariane Briegel,
  • Grant J. Jensen

DOI
https://doi.org/10.1038/s41467-020-15736-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Bacterial chemosensory systems are grouped into 17 flagellar classes (F1-17). Here the authors employ electron cryotomography and comparative genomics to characterise the chemosensory arrays in γ-proteobacteria and identify a structural distinct form of F7 that was repurposed to a different biological role over the course of its evolution.