The Blood-Brain Barrier in Both Humans and Rats: A Perspective From 3D Imaging

Aiwen Chen; Gavin Volpato; Alice Pong; Emma Schofield; Jun Huang; Zizhao Qiu; George Paxinos; Huazheng Liang

doi:10.1155/2024/4482931

International Journal of Biomedical Imaging (Jan 2024)

The Blood-Brain Barrier in Both Humans and Rats: A Perspective From 3D Imaging

Aiwen Chen,
Gavin Volpato,
Alice Pong,
Emma Schofield,
Jun Huang,
Zizhao Qiu,
George Paxinos,
Huazheng Liang

Affiliations

Aiwen Chen: Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation
Gavin Volpato: Department of Brain Structure and Function
Alice Pong: Department of Brain Structure and Function
Emma Schofield: Department of Brain Structure and Function
Jun Huang: School of Chemical and Biomolecular Engineering
Zizhao Qiu: Centre of Life Science
George Paxinos: Department of Brain Structure and Function
Huazheng Liang: Translational Research Institute of Brain and Brain-Like Intelligence

DOI: https://doi.org/10.1155/2024/4482931
Journal volume & issue: Vol. 2024

Abstract

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Conclusions: The present study demonstrated the 3D structure of both the human and rat BBB, which is discrepant from the 2D one. Tissue clearing and 3D imaging are promising techniques to answer more questions about the real structure of biological specimens.

Published in International Journal of Biomedical Imaging

ISSN: 1687-4188 (Print); 1687-4196 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine; Medicine: Medicine (General): Medical technology
Website: https://onlinelibrary.wiley.com/journal/2973

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