Differentiation of Benign and Malignant Kidney Masses via Inflammation Parameters

Abstract

Objective:Despite the recent advances in imaging methods, the rate of 10-20% is still insufficient in predicting the pathology of renal masses. Therefore, we aimed to examine whether hematological inflammatory markers were useful in predicting pathology outcome.Method:One hundred sixteen patients who were operated for kidney mass between January 2010 and October 2020 were included in the study. Retrospectively, preoperative platelets, neutrophils, lymphocytes and their rates were compared with pathology results.Results:The mean age of 116 patients included in the study was 55.36±13.93 years. While pathology results of 26 (22.4%) patients were benign, results of 90 (77.6%) patients were malignant. The neutrophil and neutrophil lymphocyte ratio were significantly lower in the benign group. According to the Fuhrman grade of renal cell carcinoma, platelet and platelet lymphocyte ratio were higher in aggressive groups, whereas lymphocyte count was lower.Conclusion:Hematological inflammatory markers are useful in predicting the pathology outcome of kidney masses before surgery.

Keywords

• blood platelets
• kidney neoplasms
• lymphocytes
• neutrophils