Developmental changes in story-evoked responses in the neocortex and hippocampus

Abstract

How does the representation of naturalistic life events change with age? Here, we analyzed fMRI data from 414 children and adolescents (5–19 years) as they watched a narrative movie. In addition to changes in the degree of inter-subject correlation (ISC) with age in sensory and medial parietal regions, we used a novel measure (between-group ISC) to reveal age-related shifts in the responses across the majority of the neocortex. Over the course of development, brain responses became more discretized into stable and coherent events and shifted earlier in time to anticipate upcoming perceived event transitions, measured behaviorally in an age-matched sample. However, hippocampal responses to event boundaries actually decreased with age, suggesting a shifting division of labor between episodic encoding processes and schematic event representations between the ages of 5 and 19.

Keywords

• child development
• inter-subject correlation
• event segmentation
• hippocampus
• hidden Markov model
• narrative