Diagnostics (Jan 2021)

Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review

  • Urszula Maria Ciochon,
  • Grethe Schmidt,
  • Ruben Juhl Jensen,
  • Anand C. Loya,
  • Lars Birger Lönn,
  • Nitesh Shekhrajka

DOI
https://doi.org/10.3390/diagnostics11010062
Journal volume & issue
Vol. 11, no. 1
p. 62

Abstract

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Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and immunohistochemical analysis on the histologic material eventually coupled with demonstration of NAB2-STAT6 gene fusion by next generation sequencing (NGS) analysis. Tumor removal with clear surgical margins is sufficient for complete cure in most cases. Percutaneous transcatheter embolization in well-vascularized lesions may minimize the risk of bleeding during subsequent removal. In this article we present a rare case of SFT arising from the external auditory canal and treated with preoperative endovascular arterial embolization. A literature review with focus on diagnostics and treatment of this entity in the head and neck region is following.

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