siRNA Seed Region Is Divided into Two Functionally Different Domains in RNA Interference in Response to 2′-OMe Modifications

• Yoshiaki Kobayashi,
• Daiki Fukuhara,
• Dai Akase,
• Misako Aida,
• Kumiko Ui-Tei

Affiliations

Yoshiaki Kobayashi

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan

Daiki Fukuhara

Center for Quantum Life Sciences and Department of Chemistry, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, Japan

Dai Akase

Center for Quantum Life Sciences and Department of Chemistry, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, Japan

Misako Aida

Center for Quantum Life Sciences and Department of Chemistry, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, Japan

Kumiko Ui-Tei

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan