mSphere (Jun 2021)

IMMUNO-COV v2.0: Development and Validation of a High-Throughput Clinical Assay for Measuring SARS-CoV-2-Neutralizing Antibody Titers

  • Rianna Vandergaast,
  • Timothy Carey,
  • Samantha Reiter,
  • Chase Lathrum,
  • Patrycja Lech,
  • Clement Gnanadurai,
  • Michelle Haselton,
  • Jason Buehler,
  • Riya Narjari,
  • Luke Schnebeck,
  • Anne Roesler,
  • Kara Sevola,
  • Lukkana Suksanpaisan,
  • Alice Bexon,
  • Shruthi Naik,
  • Bethany Brunton,
  • Scott C. Weaver,
  • Grace Rafael,
  • Sheryl Tran,
  • Alina Baum,
  • Christos A. Kyratsous,
  • Kah Whye Peng,
  • Stephen J. Russell

DOI
https://doi.org/10.1128/mSphere.00170-21
Journal volume & issue
Vol. 6, no. 3

Abstract

Read online

Since its emergence at the end of 2019, SARS-CoV-2, the causative agent of COVID-19, has caused over 100 million infections and 2.4 million deaths worldwide. Recently, countries have begun administering approved COVID-19 vaccines, which elicit strong immune responses and prevent disease in most vaccinated individuals.