The association and potential mechanisms between ambient particulate matter and chronic kidney disease
Chen Rui,
Chu Hong,
Li Pengfei,
Wang Jinwei,
Wang Fulin,
Yang Chao,
Zhang Luxia
Affiliations
Chen Rui
Peking University First Hospital, Beijing 100034, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China
Chu Hong
Peking University First Hospital, Beijing 100034, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China
Li Pengfei
Advanced Institute of Information Technology, Peking University, Hangzhou 311215, Zhejiang, China
Wang Jinwei
Peking University First Hospital, Beijing 100034, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China
Wang Fulin
Peking University First Hospital, Beijing 100034, China;Institute of Medical Technology, Peking University Health Science Center, Beijing 100191, China
Yang Chao
Peking University First Hospital, Beijing 100034, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China; Advanced Institute of Information Technology, Peking University, Hangzhou 311215, Zhejiang, China
Zhang Luxia
Peking University First Hospital, Beijing 100034, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China; Advanced Institute of Information Technology, Peking University, Hangzhou 311215, Zhejiang, China;National Institute of Health Data Science at Peking University, Beijing 100191, China; Research Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing 100191, China
The effect of air pollution on human health becomes a severe public health challenge due to rapid development in global economy and industrialized urbanization. Particulate matter (PM) is one of the major air pollutants and its renal toxicity has gained accumulating attention. Epidemiological evidence identified that the PM contributes to the development and progression of chronic kidney disease (CKD). This paper reviews the effects of PMs (PM10, PM2.5 and PM1) on CKD and its underlying mechanisms, which provides evidence for control of PM and strategy of managing CKD.
