Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification

• Philip R. Lindstedt,
• Francesco A. Aprile,
• Maria J. Matos,
• Michele Perni,
• Jean B. Bertoldo,
• Barbara Bernardim,
• Quentin Peter,
• Gonzalo Jiménez-Osés,
• Tuomas P. J. Knowles,
• Christopher M. Dobson,
• Francisco Corzana,
• Michele Vendruscolo,
• Gonçalo J. L. Bernardes

Affiliations

Philip R. Lindstedt

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Francesco A. Aprile

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Maria J. Matos

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Michele Perni

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Jean B. Bertoldo

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Barbara Bernardim

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Quentin Peter

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Gonzalo Jiménez-Osés

Departamento de Química, Universidad de La Rioja, Logroño, Spain

Tuomas P. J. Knowles

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Christopher M. Dobson

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Francisco Corzana

Departamento de Química, Universidad de La Rioja, Logroño, Spain

Michele Vendruscolo

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.

Gonçalo J. L. Bernardes

Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, U.K.