Nature Communications (Dec 2017)

Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing

  • Karsten Bach,
  • Sara Pensa,
  • Marta Grzelak,
  • James Hadfield,
  • David J. Adams,
  • John C. Marioni,
  • Walid T. Khaled

DOI
https://doi.org/10.1038/s41467-017-02001-5
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 11

Abstract

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There is a need to understand how mammary epithelial cells respond to changes at various developmental stages. Here, the authors use single-cell RNA sequencing of mammary epithelial cells at different adult developmental stages, identifying different cell types and charting their developmental trajectory.