Radiation Oncology (Nov 2022)

Characterization and dynamics of the soluble immunological microenvironment in melanoma patients undergoing radiotherapy

  • Michael Oertel,
  • Katrin Borrmann,
  • Andrea Baehr,
  • Hans Theodor Eich,
  • Burkhard Greve

DOI
https://doi.org/10.1186/s13014-022-02167-3
Journal volume & issue
Vol. 17, no. 1
pp. 1 – 5

Abstract

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Highlights Malignant melanoma patients reveal a characteristic and distinct immunological pattern. Elevated levels of soluble PD-L1 induced by previous immunotherapy were found. There were decreased levels of soluble PD-L2 in comparison to healthy controls. Radiotherapy did not result in significant dynamics of the soluble parameters in the (short-time) course of disease.