Nature Communications (Aug 2021)

The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors

  • Xuelei Lai,
  • Rosario Vega-Léon,
  • Veronique Hugouvieux,
  • Romain Blanc-Mathieu,
  • Froukje van der Wal,
  • Jérémy Lucas,
  • Catarina S. Silva,
  • Agnès Jourdain,
  • Jose M. Muino,
  • Max H. Nanao,
  • Richard Immink,
  • Kerstin Kaufmann,
  • François Parcy,
  • Cezary Smaczniak,
  • Chloe Zubieta

DOI
https://doi.org/10.1038/s41467-021-24978-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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MADS transcription factors regulate multiple aspects of plant development. Here the authors show that the intervening I domain is conserved in both type I and type II plant MADS lineages and contributes to the functional identity of the protein by influencing both DNA binding activity and dimerisation specificity.