Polish Journal of Microbiology (Feb 2022)

Helicobacter pylori and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – A Pilot Study

  • Dzikowiec Magdalena,
  • Lik Przemysław,
  • Kiszałkiewicz Justyna,
  • Kuczyńska Aleksandra,
  • Mordalski Marek,
  • Nejc Dariusz,
  • Piekarski Janusz,
  • Brzeziańska-Lasota Ewa,
  • Pastuszak-Lewandoska Dorota

DOI
https://doi.org/10.33073/pjm-2022-004
Journal volume & issue
Vol. 71, no. 1
pp. 123 – 129

Abstract

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The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to Helicobacter pylori and Epstein-Barr virus, both of which cause gastritis and can lead to tumor development. In co-infection, the inflammatory process is much more intense. We assessed the seroprevalence towards H. pylori and EBV in 32 patients with diagnosed gastric cancer. H. pylori antibodies were found in 69% patients, and anti-EBV – in all of them. The study confirmed that co-infection of H. pylori and EBV seems to be important in etiopathology of gastric cancer.

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